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  1. Home/
  2. Salaries/
  3. Senior Healthcare AI Engineer/
  4. Sioux Falls

Senior Healthcare AI Engineer.

Sioux Falls.

$173,000

median salary, 16% below the national average

$135,000 to $224,000. Last updated April 2026.

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Data points to own the conversation.

Sioux Falls is 15% cheaper than the national average. For Senior Healthcare AI Engineers, that shakes out to a median of $173,000, with the full range spanning $135,000 to $224,000. Model complexity, data pipeline scale, and infrastructure cost optimization are the primary drivers. Know the range before you walk in.

Salary range

25th Percentile

$135,000

per year

Median

$173,000

per year

75th Percentile

$224,000

per year

Where do you fall?

$135,000$224,000

Salary by experience

The gap between entry and lead level is typically $156,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$112,000

to $138,000

Mid (3-5 yrs)

$147,000

to $182,000

Senior (6-9 yrs)

$190,000

to $225,000

Lead (10+ yrs)

$216,000

to $268,000

Salary trend

+7% YoY
$132,000
2022
$141,000
2023
$151,000
2024
$162,000
2025
$173,000
2026

Total compensation

Base salary is not the full picture. Equity, bonus, and signing can add $40,000 to the total package.

Base

$173,000

Equity

$22,000

Bonus

$15,000

Signing

$3,000

Estimated total: $213,000

How Sioux Falls compares

Sioux Falls, SD

$173,000

Cost of living: 15% below average

National Average

$205,000

Sioux Falls is $32,000 below

Senior Healthcare AI Engineer salary by city

Senior Healthcare AI Engineer salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$289,000$225,000 – $374,0001.38x$209,000
San Francisco, CA$282,000$220,000 – $366,0001.35x$209,000
Honolulu, HI$272,000$212,000 – $353,0001.30x$209,000
New York, NY$270,000$211,000 – $351,0001.28x$211,000
Washington DC, DC$267,000$208,000 – $346,0001.25x$214,000
Arlington, VA$260,000$203,000 – $338,0001.22x$213,000
Seattle, WA$257,000$200,000 – $333,0001.24x$207,000
Jersey City, NJ$248,000$194,000 – $322,0001.20x$207,000
Boston, MA$245,000$191,000 – $318,0001.22x$201,000
Sioux Falls, SD$173,000$135,000 – $224,0000.85x$204,000

See all 81 cities for Senior Healthcare AI Engineer →

Salary by role in Sioux Falls

Salary comparison by role in Sioux Falls
RoleMedianRange
Principal Quantitative Researcher$306,000$239,000 – $398,000
Principal AI Research Scientist$298,000$232,000 – $387,000
Distinguished Engineer$292,000$221,000 – $371,000
Senior Healthcare AI Engineer$173,000$135,000 – $224,000
AI World Model Engineer$173,000$128,000 – $227,000
AI Reasoning Specialist$173,000$128,000 – $230,000
Staff Data Scientist$173,000$135,000 – $225,000
Lead Cloud Engineer$173,000$135,000 – $225,000

What you should know

The Senior Healthcare AI Engineer landscape in Sioux Falls is not what most salary sites will tell you. Sioux Falls is South Dakota's largest city and a growing financial services hub, home to major credit card operations for Citibank and Wells Fargo. The city's no state income tax and very low cost of living create exceptional take home pay ratios. Healthcare and agriculture round out the economy. Model complexity, data pipeline scale, and infrastructure cost optimization are the primary drivers. Senior Healthcare AI Engineers with experience across the full ML lifecycle, from research prototyping to production serving, earn more than those focused on a single phase. Domain expertise in high-stakes verticals like healthcare, finance, or autonomous systems adds measurable premiums.

Senior Healthcare AI Engineers earn $160,000 to $266,000. Progression splits into the IC track (staff at $318,000, principal at $359,000) or management (engineering manager at $338,000). Specialization depth and cross-team impact determine which path yields higher compensation. In Sioux Falls, your dollars stretch further. Cost of living runs 15% below the national average, which means even a median salary buys a stronger lifestyle.

Base salary is not the full picture. Equity at top-tier companies adds 30% to 60% above base salary. Annual bonuses of 15% to 25% are standard. Signing bonuses of $25,000 to $75,000 are common when changing roles. Refresher equity grants vest annually. Relocation packages and executive benefits like financial planning are typical. And on the tax side: south Dakota has no state income tax. Sioux Falls has no city income tax. This zero income tax environment is a major draw for high earners seeking maximum take home pay. When someone quotes you $173,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Use the zero income tax advantage in negotiations. Sioux Falls employers know this is a major recruiting tool and will frame compensation accordingly. The range for Senior Healthcare AI Engineers in Sioux Falls runs from $135,000 to $224,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology

Interactive

Is your offer competitive?

Enter your Senior Healthcare AI Engineer offer to see where you stand in Sioux Falls.

$

25th

$135,000

Median

$173,000

75th

$224,000

Considering a related role?

  • A AI Research Scientist in Sioux Falls earns $172,000 (1% less)
  • The highest-paying role in Sioux Falls is Principal Quantitative Researcher at $306,000

Common questions.

Production deployment experience, published research or open source contributions, and expertise with the latest model architectures command the highest premiums. Proficiency in Python, PyTorch, and cloud ML platforms is baseline. Experience with LLM fine-tuning, RLHF, and inference optimization is increasingly differentiated.

AI labs and foundation model companies pay 20% to 40% more than enterprises. Well-funded AI startups offer competitive base salaries with significant equity upside. Large tech companies provide the most stable total compensation packages with strong equity vesting schedules.

Model complexity, data pipeline scale, and infrastructure cost optimization are the primary drivers. Senior Healthcare AI Engineers with experience across the full ML lifecycle, from research prototyping to production serving, earn more than those focused on a single phase. Domain expertise in high-stakes verticals like healthcare, finance, or autonomous systems adds measurable premiums. In Sioux Falls, these factors can push compensation from the 25th percentile of $135,000 to the 75th percentile of $224,000 or beyond.

Sioux Falls's cost of living multiplier is 0.85x the national average. The adjusted median Senior Healthcare AI Engineer salary of $173,000 accounts for this. In practice, a Senior Healthcare AI Engineer earning $173,000 in Sioux Falls has roughly the same purchasing power as someone earning $203,529 in an average cost market.

Entry level Senior Healthcare AI Engineer positions in Sioux Falls typically start near $135,000. Candidates with relevant internships, certifications, or portfolio work often negotiate closer to the median of $173,000. Senior Healthcare AI Engineers earn $160,000 to $266,000.

Remote work has compressed geographic salary premiums for Senior Healthcare AI Engineers. Some Sioux Falls employers offer location adjusted pay, while others maintain local rates to attract in office talent. In Sioux Falls's moderate cost market, remote and local salaries are converging. The $135,000 to $224,000 range reflects both arrangements.

Sioux Falls is South Dakota's largest city and a growing financial services hub, home to major credit card operations for Citibank and Wells Fargo. The city's no state income tax and very low cost of living create exceptional take home pay ratios. For Senior Healthcare AI Engineers specifically, the median salary of $173,000 reflects that demand.

Senior Healthcare AI Engineer salary in other cities

Austin$205,000
Atlanta$201,000
Anchorage$222,000
Albuquerque$186,000
Arlington$260,000
Albany$205,000

Other salaries in Sioux Falls

Electrician$55,000
Edge AI Engineer$151,000
Elevator Installer / Repair$71,000
Executive Assistant$58,000

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"Senior Healthcare AI Engineer Salary in Sioux Falls, SD." Orbyt Salary Explorer, April 2026. https://www.orbytjobs.ai/salaries/senior-healthcare-ai-engineer/sioux-falls

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