Clinical Research Coordinator.
Minneapolis.
$67,000
median salary, 5% above the national average
$53,000 to $86,000. Updated for 2026.
The numbers.
Everything you need to negotiate with confidence.
If you are evaluating a Clinical Research Coordinator offer in Minneapolis, MN, here is the reality: $53,000 to $86,000, with $67,000 as the midpoint. 5% above the national average. Therapeutic area and trial phase drive the biggest pay differences. Do not accept the first number.
Salary range
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How Minneapolis compares
Minneapolis, MN
$67,000
Cost of living: 5% above average
National Average
$64,000
Minneapolis is $3,000 above
What you should know
Here is what the Clinical Research Coordinator market actually looks like in Minneapolis. Minneapolis is a Fortune 500 powerhouse with Target, UnitedHealth Group, Best Buy, and 3M headquartered in the metro. The city's strong corporate base creates consistent demand across finance, healthcare, retail tech, and supply chain roles. Quality of life is high, and employers offer competitive salaries to offset the cold winters. Therapeutic area and trial phase drive the biggest pay differences. Oncology, gene therapy, and Phase I trials pay the most due to protocol complexity. ACRP or SoCRA certification adds 8 to 12% above non-certified coordinators. Academic medical centers and large CROs in biotech hubs offer the highest salaries.
Entry-level CRCs start at $48,000 to $55,000 with a science degree. Certified CRCs with three to five years of experience earn $65,000 to $80,000. Senior CRCs or clinical research managers can reach $85,000 to $110,000 overseeing multi-site trials and regulatory submissions. In Minneapolis, cost of living sits near the national average, so the numbers you see are roughly what you keep.
Base salary is not the full picture. CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. CRO-employed coordinators may receive project completion bonuses of $2,000 to $5,000. Some pharmaceutical sponsors offer annual merit increases of 3 to 6%. And on the tax side: minnesota's top income tax rate is 9.85%, one of the highest state rates. There is no city income tax in Minneapolis, but the state burden significantly reduces take home pay. When someone quotes you $67,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Emphasize retention risk when negotiating. Minneapolis employers know that remote opportunities from warmer, lower tax states are a constant competitive threat. The range for Clinical Research Coordinators in Minneapolis runs from $53,000 to $86,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
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Negotiating in Minneapolis
Emphasize retention risk when negotiating. Minneapolis employers know that remote opportunities from warmer, lower tax states are a constant competitive threat.