Respiratory Therapist.
St. Louis.
$58,000
median salary, 9% below the national average
$49,000 to $68,000. Updated for 2026.
The numbers.
Everything you need to negotiate with confidence.
The median Respiratory Therapist salary in St. Louis is $58,000, 9% below the national average. Entry level starts near $49,000. Experienced professionals push past $68,000. St. That spread is your negotiation window.
Salary range
Tap to place your salary
How St. Louis compares
St. Louis, MO
$58,000
Cost of living: 10% below average
National Average
$64,000
St. Louis is $6,000 below
What you should know
Before you negotiate a Respiratory Therapist offer in St. Louis, understand the terrain. St. Louis offers one of the most affordable major metro areas in the country, with a strong base in healthcare, financial services, and manufacturing. The region's anchor employers include Boeing, Centene, and Washington University's medical campus. A growing biotech and plant sciences corridor centered on the Cortex Innovation District is attracting new investment and talent. Shift differentials for nights, weekends, and holidays contribute significantly to total earnings. RTs working in ICU or neonatal units earn more than those in general floor care. The RRT credential is expected for most positions, and additional certifications in pulmonary function or transport add incremental pay.
Entry-level RTs earn $52,000 to $58,000 with the RRT credential. Experienced RTs in critical care reach $65,000 to $75,000 after five to seven years. Lead RTs or department supervisors can earn $78,000 to $92,000 with management responsibilities included. In St. Louis, cost of living sits near the national average, so the numbers you see are roughly what you keep.
Base salary is not the full picture. Respiratory therapists receive shift differentials of $3 to $8 per hour, overtime opportunities, and comprehensive benefits. Some hospitals offer certification bonuses and tuition reimbursement for advanced degrees or specialty credentials. And on the tax side: missouri's top income tax rate is about 4.8%, and St. Louis City adds a 1% earnings tax. The low base cost of living means your after tax salary still stretches further than in most metros. When someone quotes you $58,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Emphasize your willingness to work in person at Cortex or the BJC campus. St. Louis employers offer higher packages for candidates who commit to the local innovation hubs. The range for Respiratory Therapists in St. Louis runs from $49,000 to $68,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Top industries in St. Louis
Negotiating in St. Louis
Emphasize your willingness to work in person at Cortex or the BJC campus. St. Louis employers offer higher packages for candidates who commit to the local innovation hubs.