Clinical Research Coordinator.
Houston.
$62,000
median salary, 3% below the national average
$49,000 to $80,000. Updated for 2026.
The numbers.
Everything you need to negotiate with confidence.
Here is what Clinical Research Coordinators actually make in Houston: $49,000 at the 25th percentile, $62,000 at the median, and $80,000 at the 75th. That is 3% below the national average. Houston's economy is deeply rooted in energy, with a growing presence in healthcare, aerospace, and technology. The number on your offer letter will depend on what you bring and how you ask.
Salary range
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How Houston compares
Houston, TX
$62,000
Cost of living: 3% below average
National Average
$64,000
Houston is $2,000 below
What you should know
Before you negotiate a Clinical Research Coordinator offer in Houston, understand the terrain. Houston's economy is deeply rooted in energy, with a growing presence in healthcare, aerospace, and technology. The Texas Medical Center is the world's largest, driving massive demand for clinical and research roles. Houston's low cost of living and no state income tax make it an attractive destination for professionals seeking strong purchasing power. Therapeutic area and trial phase drive the biggest pay differences. Oncology, gene therapy, and Phase I trials pay the most due to protocol complexity. ACRP or SoCRA certification adds 8 to 12% above non-certified coordinators. Academic medical centers and large CROs in biotech hubs offer the highest salaries.
Entry-level CRCs start at $48,000 to $55,000 with a science degree. Certified CRCs with three to five years of experience earn $65,000 to $80,000. Senior CRCs or clinical research managers can reach $85,000 to $110,000 overseeing multi-site trials and regulatory submissions. In Houston, cost of living sits near the national average, so the numbers you see are roughly what you keep.
Base salary is not the full picture. CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. CRO-employed coordinators may receive project completion bonuses of $2,000 to $5,000. Some pharmaceutical sponsors offer annual merit increases of 3 to 6%. And on the tax side: texas has no state income tax, giving Houston workers strong take home pay. The city's overall cost of living is below the national average, further stretching your salary. When someone quotes you $62,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Emphasize industry specialization in energy or healthcare. Houston employers pay significant premiums for domain expertise in these sectors over generalist candidates. The range for Clinical Research Coordinators in Houston runs from $49,000 to $80,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Top industries in Houston
Negotiating in Houston
Emphasize industry specialization in energy or healthcare. Houston employers pay significant premiums for domain expertise in these sectors over generalist candidates.