AI Drug Discovery Scientist.
Baltimore.
$172,000
median salary, 9% above the national average
$131,000 to $218,000. Last updated April 2026.
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Data points to own the conversation.
AI Drug Discovery Scientist pay in Baltimore ranges from $131,000 to $218,000 in 2026. The median is $172,000, 9% above the national average. Baltimore's economy is anchored by Johns Hopkins University and Hospital, one of the largest employers in the state. Every dollar in that range is negotiable if you come prepared.
Salary range
Where do you fall?
Salary by experience
The gap between entry and lead level is typically $155,000. Where you land depends on years of experience and what you bring to the table.
Entry (0-2 yrs)
$112,000
to $138,000
Mid (3-5 yrs)
$146,000
to $181,000
Senior (6-9 yrs)
$189,000
to $224,000
Lead (10+ yrs)
$215,000
to $267,000
Salary trend
+8% YoYTotal compensation
Base salary is not the full picture. Equity, bonus, and signing can add $71,000 to the total package.
Base
$172,000
Equity
$43,000
Bonus
$18,000
Signing
$10,000
Estimated total: $243,000
How Baltimore compares
Baltimore, MD
$172,000
Cost of living: 8% above average
National Average
$158,000
Baltimore is $14,000 above
AI Drug Discovery Scientist salary by city
Salary by role in Baltimore
What you should know
Before you negotiate a AI Drug Discovery Scientist offer in Baltimore, understand the terrain. Baltimore's economy is anchored by Johns Hopkins University and Hospital, one of the largest employers in the state. The city has strong cybersecurity, defense, and biotech sectors, benefiting from proximity to NSA, Fort Meade, and NIH. The port of Baltimore also drives significant logistics and trade employment. Compensation reflects the combination of computational biology expertise and ML engineering skills. Scientists who can apply deep learning to molecular design, protein structure prediction, and ADMET modeling command premiums. Publication record in both ML and drug discovery venues adds significant value. Pharma industry experience amplifies salary above pure tech roles.
Postdoc scientists start at $110,000 to $130,000. Mid-level scientists with deployed drug discovery models reach $148,000 to $175,000. Senior scientists leading AI drug discovery programs earn $185,000 to $230,000. Directors of computational drug discovery at pharma companies can reach $260,000 to $340,000 in total compensation. In Baltimore, cost of living sits near the national average, so the numbers you see are roughly what you keep.
Base salary is not the full picture. Equity at biotech AI startups can be substantial, adding $30,000 to $100,000 in annual value. Pharma companies offer bonuses of 15% to 25% tied to pipeline milestones. Some organizations provide milestone bonuses when AI-discovered compounds advance through clinical trials. Benefits typically include generous research budgets. And on the tax side: maryland's top income tax rate is 5.75%, and Baltimore City adds a local income tax of 3.2%. The combined burden is among the higher ones, but federal and defense salaries compensate. When someone quotes you $172,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: A security clearance is extremely valuable in the Baltimore corridor. Cleared professionals earn 20 to 30% more, and the NSA and defense contractor presence drives constant demand. The range for AI Drug Discovery Scientists in Baltimore runs from $131,000 to $218,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology
Considering a related role?
- A AI Enablement & Literacy Lead in Baltimore earns $171,000 (1% less)
- The highest-paying role in Baltimore is Distinguished Engineer at $349,000
Common questions.
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