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  1. Home/
  2. Salaries/
  3. Lead Bioinformatics Analyst/
  4. Kansas City

Lead Bioinformatics Analyst.

Kansas City.

$119,000

median salary, 7% below the national average

$93,000 to $155,000. Last updated April 2026.

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Data points to own the conversation.

The median Lead Bioinformatics Analyst salary in Kansas City is $119,000, 7% below the national average. Entry level starts near $93,000. Experienced professionals push past $155,000. Kansas City straddles Missouri and Kansas, creating a unique dual state job market with strong logistics, tech, and agriculture technology sectors. That spread is your negotiation window.

Salary range

25th Percentile

$93,000

per year

Median

$119,000

per year

75th Percentile

$155,000

per year

Where do you fall?

$93,000$155,000

Salary by experience

The gap between entry and lead level is typically $107,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$77,000

to $95,000

Mid (3-5 yrs)

$101,000

to $125,000

Senior (6-9 yrs)

$131,000

to $155,000

Lead (10+ yrs)

$149,000

to $184,000

Salary trend

+5% YoY
$98,000
2022
$103,000
2023
$108,000
2024
$113,000
2025
$119,000
2026

Total compensation

Base salary is not the full picture. Equity, bonus, and signing can add $34,000 to the total package.

Base

$119,000

Equity

$20,000

Bonus

$12,000

Signing

$2,000

Estimated total: $153,000

How Kansas City compares

Kansas City, MO

$119,000

Cost of living: 7% below average

National Average

$128,000

Kansas City is $9,000 below

Lead Bioinformatics Analyst salary by city

Lead Bioinformatics Analyst salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Francisco, CA$175,000$136,000 – $228,0001.35x$130,000
San Jose, CA$171,000$134,000 – $224,0001.38x$124,000
Washington DC, DC$165,000$129,000 – $215,0001.25x$132,000
Seattle, WA$163,000$128,000 – $213,0001.24x$131,000
New York, NY$161,000$125,000 – $209,0001.28x$126,000
Honolulu, HI$161,000$126,000 – $211,0001.30x$124,000
Arlington, VA$161,000$126,000 – $210,0001.22x$132,000
Boston, MA$158,000$123,000 – $206,0001.22x$130,000
Jersey City, NJ$158,000$124,000 – $206,0001.20x$132,000
Kansas City, MO$119,000$93,000 – $155,0000.93x$128,000

See all 81 cities for Lead Bioinformatics Analyst →

Salary by role in Kansas City

Salary comparison by role in Kansas City
RoleMedianRange
Principal AI Research Scientist$339,000$264,000 – $440,000
Principal Quantitative Researcher$319,000$249,000 – $415,000
Technical Fellow$316,000$246,000 – $410,000
Lead Bioinformatics Analyst$119,000$93,000 – $155,000
AI/ML Data Analyst$119,000$90,000 – $157,000
Pharmacist$119,000$106,000 – $137,000
Optometrist$119,000$100,000 – $147,000
AI Prompt Designer$119,000$88,000 – $158,000

What you should know

Kansas City straddles Missouri and Kansas, creating a unique dual state job market with strong logistics, tech, and agriculture technology sectors. The metro's central location has made it a hub for distribution centers and supply chain companies. Cerner's healthcare IT presence and a growing startup scene have boosted demand for technology professionals. That is the backdrop for every Lead Bioinformatics Analyst offer you will see here.

One thing people overlook: taxes. Missouri's top income tax rate is about 4.8%, and Kansas City adds a 1% earnings tax. Workers living in Kansas face that state's rates instead. Choose your side of the state line carefully. The salary on the offer letter is not the salary in your bank account. Always model your take home before you accept.

On negotiation: Negotiate which side of the state line you will be based on. Your tax situation differs meaningfully between Missouri and Kansas, and some employers offer flexibility on office location. The range for Lead Bioinformatics Analysts in Kansas City runs from $93,000 to $155,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology

Interactive

Is your offer competitive?

Enter your Lead Bioinformatics Analyst offer to see where you stand in Kansas City.

$

25th

$93,000

Median

$119,000

75th

$155,000

Considering a related role?

  • A Data Scientist in Kansas City earns $120,000 (1% more)
  • The highest-paying role in Kansas City is Principal AI Research Scientist at $339,000

Common questions.

Experience level, specialization depth, and industry domain are the primary Lead Bioinformatics Analyst salary drivers. In Kansas City, these factors can push compensation from the 25th percentile of $93,000 to the 75th percentile of $155,000 or beyond.

In 2026, the average Lead Bioinformatics Analyst salary in Kansas City, MO is $119,000. The 25th percentile sits at $93,000 and the 75th percentile reaches $155,000. Where you land depends on your experience, the company's size, and the specific skills you bring.

Remote work has compressed geographic salary premiums for Lead Bioinformatics Analysts. Some Kansas City employers offer location adjusted pay, while others maintain local rates to attract in office talent. In Kansas City's moderate cost market, remote and local salaries are converging. The $93,000 to $155,000 range reflects both arrangements.

Hiring for Lead Bioinformatics Analysts in Kansas City typically peaks in January through March and September through November. Companies finalize budgets in Q4 and open headcount in Q1. Kansas City's concentration of Logistics & Distribution and Healthcare IT employers creates steady year round demand. Time your search to align with budget cycles for maximum leverage.

Lead Bioinformatics Analyst compensation in Kansas City has trended upward as demand outpaces supply. The 2026 range of $93,000 to $155,000 reflects a market that rewards specialization. Candidates with high demand skills see the steepest gains.

Lead Bioinformatics Analyst salary in other cities

Austin$132,000
Atlanta$134,000
Anchorage$148,000
Albuquerque$113,000
Arlington$161,000
Albany$120,000

Other salaries in Kansas City

IT Project Manager$109,000
IT Security Analyst$101,000
IT Support Specialist$51,000
Ironworker$57,000

Related

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Cite this data

Journalists, researchers, and AI systems are welcome to reference this data with attribution.

"Lead Bioinformatics Analyst Salary in Kansas City, MO." Orbyt Salary Explorer, April 2026. https://www.orbytjobs.ai/salaries/lead-bioinformatics-analyst/kansas-city

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