Lead Genomics Data Scientist Salary.
Across 81 U.S. cities.
$189,000
national median salary
$147,000 to $246,000. Last updated April 2026.
Highest Paying
$265,000
San Francisco, CA
Best Purchasing Power
$197,000
Arlington, VA
Lowest Paying
$145,000
Jackson, MS
Salary data sourced from SEC filings, H-1B Labor Condition Applications (DOL), Bureau of Labor Statistics Occupational Employment and Wage Statistics, and aggregated job postings across 50+ platforms. Ranges reflect 25th to 75th percentile for full-time positions. Cost-of-living adjustments use Bureau of Economic Analysis Regional Price Parities (2025 index). Last updated April 2026. Baseline derived from BLS SOC 15-2051. Full methodology.
The average Lead Genomics Data Scientist salary in the United States is $189,000 in 2026, with the full range spanning $147,000 at the 25th percentile to $246,000 at the 75th. San Francisco pays the most at $265,000, while Arlington offers the best purchasing power after cost-of-living adjustments. Lead Genomics Data Scientist compensation is driven by publication record, domain specialization, and whether the work involves production model training or applied research.
Lead Genomics Data Scientist salary by city
Skills that increase Lead Genomics Data Scientist pay
The skills below command measurable salary premiums for Lead Genomics Data Scientists based on job posting data. Learning the top skill here could add $26,460 to your annual compensation.
≈ +$26,460 per year
≈ +$24,570 per year
≈ +$22,680 per year
≈ +$20,790 per year
≈ +$18,900 per year
≈ +$18,900 per year
≈ +$18,900 per year
≈ +$17,010 per year
What you should know
Lead Genomics Data Scientist compensation is driven by publication record, domain specialization, and whether the work involves production model training or applied research. Base salary carries most of the total compensation, with bonuses adding roughly 12% in a typical year. Within tech-sector Lead Genomics Data Scientists specifically, employer tier (FAANG and frontier-AI labs vs mid-stage startups vs traditional enterprise) drives 67%+ variance across the compensation band.
Lead Genomics Data Scientists progress Research Engineer → Senior → Staff → Principal → Distinguished over 8 to 15 years. Frontier-AI labs compress this ladder — a strong PhD can land at L5/Senior directly. The VP Research track diverges around year 10 for those who choose to lead labs. For Lead Genomics Data Scientists specifically, the seniority anchor typically means 7 to 12 years of experience with demonstrated independent scope.
Total compensation for Lead Genomics Data Scientists runs roughly $212K at median when factoring base + typical bonus (~12% of base). Base salary carries most of the compensation; benefits (healthcare, 401(k) match, PTO) add an estimated 15–25% in imputed value on top. At tech companies specifically, equity and sign-on are often the largest delta between offers — two roles with matching base can differ by $100K+ at total when equity is included.
Total compensation breakdown
Salary by company size
Remote salary adjustment
Remote Lead Genomics Data Scientists typically earn $170,000 (10% less than on-site). This reflects location-adjusted pay policies at companies using geographic salary bands. Some companies pay flat national rates regardless of location.
Are you a Lead Genomics Data Scientist?
Share your real compensation anonymously. Help build the most accurate salary dataset for this role. Your data is never individually exposed.
Related tools