Lead Pathology AI Engineer.
Louisville.
$196,000
median salary, 9% below the national average
$152,000 to $255,000. Last updated April 2026.
Get the job.
Data points to own the conversation.
Louisville is 12% cheaper than the national average. For Lead Pathology AI Engineers, that shakes out to a median of $196,000, with the full range spanning $152,000 to $255,000. Compensation reflects specialization depth, production deployment scale, and the maturity of the AI systems being built. Know the range before you walk in.
Salary range
Where do you fall?
Salary by experience
The gap between entry and lead level is typically $177,000. Where you land depends on years of experience and what you bring to the table.
Entry (0-2 yrs)
$127,000
to $157,000
Mid (3-5 yrs)
$167,000
to $206,000
Senior (6-9 yrs)
$216,000
to $255,000
Lead (10+ yrs)
$245,000
to $304,000
Salary trend
+4% YoYTotal compensation
Base salary is not the full picture. Equity, bonus, and signing can add $46,000 to the total package.
Base
$196,000
Equity
$25,000
Bonus
$17,000
Signing
$4,000
Estimated total: $242,000
How Louisville compares
Louisville, KY
$196,000
Cost of living: 12% below average
National Average
$216,000
Louisville is $20,000 below
Lead Pathology AI Engineer salary by city
Salary by role in Louisville
What you should know
Here is what the Lead Pathology AI Engineer market actually looks like in Louisville. Louisville is home to UPS Worldport, the world's largest automated package handling facility, making it a logistics and supply chain powerhouse. The city also has strong healthcare and bourbon distillery industries. Its central location and affordable cost of living make it attractive for distribution and operations roles. Compensation reflects specialization depth, production deployment scale, and the maturity of the AI systems being built. Lead Pathology AI Engineers who have shipped models serving millions of users command the highest premiums. Employer type matters significantly: AI labs and foundation model companies pay 20% to 40% more than enterprises adopting AI for internal use.
Entry-level Lead Pathology AI Engineers start near $168,000. Mid-career professionals with three to five years of experience reach $216,000 to $281,000. Senior-level roles command $276,000 to $335,000. Management transitions to director-level positions offer $356,000 and above. In Louisville, your dollars stretch further. Cost of living runs 12% below the national average, which means even a median salary buys a stronger lifestyle.
Base salary is not the full picture. Equity at top-tier companies adds 30% to 60% above base salary. Annual bonuses of 15% to 25% are standard. Signing bonuses of $25,000 to $75,000 are common when changing roles. Refresher equity grants vest annually. Relocation packages and executive benefits like financial planning are typical. And on the tax side: kentucky has a flat 4% state income tax. Louisville has an occupational tax of about 2.2%. The combined rate is moderate, and the low cost of living offsets the local tax. When someone quotes you $196,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Leverage UPS and the logistics corridor when negotiating. Supply chain and operations professionals command premiums in Louisville's distribution heavy economy. The range for Lead Pathology AI Engineers in Louisville runs from $152,000 to $255,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology
Considering a related role?
- A Director of Engineering in Louisville earns $197,000 (1% more)
- The highest-paying role in Louisville is Senior VP of Security at $305,000
Common questions.
Lead Pathology AI Engineer salary in other cities
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