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  1. Home/
  2. Salaries/
  3. Medical Imaging AI Specialist/
  4. Knoxville

Medical Imaging AI Specialist.

Knoxville.

$171,000

median salary, 10% below the national average

$128,000 to $223,000. Last updated April 2026.

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Data points to own the conversation.

If you are evaluating a Medical Imaging AI Specialist offer in Knoxville, TN, here is the reality: $128,000 to $223,000, with $171,000 as the midpoint. 10% below the national average. Deep knowledge of medical image analysis, FDA regulatory pathways, and clinical validation methodologies drives top compensation. Do not accept the first number.

Salary range

25th Percentile

$128,000

per year

Median

$171,000

per year

75th Percentile

$223,000

per year

Where do you fall?

$128,000$223,000

Salary by experience

The gap between entry and lead level is typically $154,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$111,000

to $137,000

Mid (3-5 yrs)

$145,000

to $180,000

Senior (6-9 yrs)

$188,000

to $222,000

Lead (10+ yrs)

$214,000

to $265,000

Salary trend

+4% YoY
$146,000
2022
$152,000
2023
$158,000
2024
$164,000
2025
$171,000
2026

Total compensation

Base salary is not the full picture. Equity, bonus, and signing can add $47,000 to the total package.

Base

$171,000

Equity

$27,000

Bonus

$17,000

Signing

$3,000

Estimated total: $218,000

How Knoxville compares

Knoxville, TN

$171,000

Cost of living: 11% below average

National Average

$190,000

Knoxville is $19,000 below

Medical Imaging AI Specialist salary by city

Medical Imaging AI Specialist salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$262,000$196,000 – $342,0001.38x$190,000
Honolulu, HI$247,000$185,000 – $322,0001.30x$190,000
New York, NY$246,000$184,000 – $321,0001.28x$192,000
San Francisco, CA$246,000$184,000 – $321,0001.35x$182,000
Seattle, WA$240,000$180,000 – $314,0001.24x$194,000
Washington DC, DC$233,000$174,000 – $304,0001.25x$186,000
Boston, MA$232,000$173,000 – $303,0001.22x$190,000
Arlington, VA$227,000$170,000 – $297,0001.22x$186,000
Jersey City, NJ$221,000$165,000 – $289,0001.20x$184,000
Knoxville, TN$171,000$128,000 – $223,0000.89x$192,000

See all 81 cities for Medical Imaging AI Specialist →

Salary by role in Knoxville

Salary comparison by role in Knoxville
RoleMedianRange
Technical Fellow$324,000$253,000 – $421,000
Principal AI Research Scientist$321,000$250,000 – $417,000
Principal Quantitative Researcher$312,000$243,000 – $405,000
Medical Imaging AI Specialist$171,000$128,000 – $223,000
Agentic Orchestrator$171,000$128,000 – $222,000
AI Performance Engineer$171,000$130,000 – $224,000
GPU Cluster Manager$171,000$130,000 – $224,000
Responsible AI Lead$171,000$129,000 – $224,000

What you should know

The Medical Imaging AI Specialist landscape in Knoxville is not what most salary sites will tell you. Knoxville benefits from the presence of Oak Ridge National Laboratory, the University of Tennessee, and the Tennessee Valley Authority. The national lab drives strong demand for research scientists, engineers, and data analysts. No state income tax and affordable living make it an attractive value proposition. Deep knowledge of medical image analysis, FDA regulatory pathways, and clinical validation methodologies drives top compensation. Specialists who understand radiology workflows and can navigate the 510(k) or De Novo approval process are extremely rare. Experience with specific modalities like CT, MRI, pathology, or ultrasound AI adds significant premiums.

Junior medical imaging engineers start at $115,000 to $150,000. Mid level specialists with regulatory submission experience earn $170,000 to $215,000. Senior specialists reach $220,000 to $275,000. VP of AI at medical imaging companies can exceed $350,000 in total compensation with equity. In Knoxville, your dollars stretch further. Cost of living runs 11% below the national average, which means even a median salary buys a stronger lifestyle.

Base salary is not the full picture. Equity at medical AI startups adds 20 to 40% of total compensation. Performance bonuses of 15 to 25% are standard. Signing bonuses of $25,000 to $75,000 are common. Benefits often include continuing medical education credits and conference travel budgets. And on the tax side: tennessee has no state income tax on wages. Knoxville has no city income tax. This zero income tax environment combined with very affordable housing creates excellent purchasing power. When someone quotes you $171,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Highlight Oak Ridge National Lab and DOE experience. National lab affiliations and security clearances command significant premiums in the Knoxville area. The range for Medical Imaging AI Specialists in Knoxville runs from $128,000 to $223,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology

Interactive

Is your offer competitive?

Enter your Medical Imaging AI Specialist offer to see where you stand in Knoxville.

$

25th

$128,000

Median

$171,000

75th

$223,000

Considering a related role?

  • A AI Solutions Architect in Knoxville earns $170,000 (1% less)
  • The highest-paying role in Knoxville is Technical Fellow at $324,000
  • See all ai healthcare roles tracked in Orbyt Intelligence

Common questions.

Engineers with direct experience navigating FDA submissions earn 20 to 35% more than those without. Understanding clinical validation study design, real world evidence requirements, and post market surveillance is extremely valuable. Companies developing FDA cleared products will pay significant premiums for specialists who can reduce regulatory risk and accelerate time to market.

A medical degree is not required but clinical collaborator experience is highly valued. Engineers who can communicate effectively with radiologists and understand clinical workflows earn more. The most common path combines a PhD in computer vision or biomedical engineering with industry experience at a medical AI company. Clinical rotations or research partnerships boost credibility.

It depends on the position and employer. Many Medical Imaging AI Specialists in Knoxville are classified as exempt salaried employees without overtime eligibility. However, equity at medical ai startups adds 20 to 40% of total compensation. When evaluating the $128,000 to $223,000 range, ask about the total compensation structure during negotiation.

Medical Imaging AI Specialist compensation in Knoxville has trended upward as demand outpaces supply. The 2026 range of $128,000 to $223,000 reflects a market that rewards specialization. Deep knowledge of medical image analysis, FDA regulatory pathways, and clinical validation methodologies drives top compensation.

Relevant certifications can add 5 to 15% to a Medical Imaging AI Specialist's base salary in Knoxville. Specifically, deep knowledge of medical image analysis, fda regulatory pathways, and clinical validation methodologies drives top compensation. In a market where the range spans $128,000 to $223,000, certifications often bridge the gap between the 50th and 75th percentile.

Knoxville benefits from the presence of Oak Ridge National Laboratory, the University of Tennessee, and the Tennessee Valley Authority. The national lab drives strong demand for research scientists, engineers, and data analysts. For Medical Imaging AI Specialists specifically, the median salary of $171,000 reflects that demand.

Medical Imaging AI Specialist salary in other cities

Austin$194,000
Atlanta$198,000
Anchorage$217,000
Albuquerque$172,000
Arlington$227,000
Albany$177,000

Other salaries in Knoxville

Electrician$57,000
Edge AI Engineer$160,000
Elevator Installer / Repair$72,000
Executive Assistant$65,000

Related salary pages

Jump to nearby roles and cities most relevant to Medical Imaging AI Specialists in Knoxville.

  • ElectricianKnoxville, TN$57,000
  • Edge AI EngineerKnoxville, TN$160,000
  • Medical Imaging AI SpecialistAustin, TX$194,000
  • Medical Imaging AI SpecialistAtlanta, GA$198,000
  • ElectricianAustin, TX$68,000
  • Edge AI EngineerAtlanta, GA$180,000
  • Medical Imaging AI SpecialistAnchorage, AK$217,000
  • Elevator Installer / RepairKnoxville, TN$72,000

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"Medical Imaging AI Specialist Salary in Knoxville, TN." Orbyt Salary Explorer, April 2026. https://www.orbytjobs.ai/salaries/medical-imaging-ai-specialist/knoxville

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