Physician Assistant.
Charleston.
$120,000
median salary, 2% above the national average
$104,000 to $141,000. Last updated April 2026.
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Data points to own the conversation.
Charleston is 2% cheaper than the national average. For Physician Assistants, that shakes out to a median of $120,000, with the full range spanning $104,000 to $141,000. Surgical subspecialties and emergency medicine pay the highest PA salaries, often 20 to 30% above primary care. Know the range before you walk in.
Salary range
Where do you fall?
Salary by experience
The gap between entry and lead level is typically $108,000. Where you land depends on years of experience and what you bring to the table.
Entry (0-2 yrs)
$78,000
to $96,000
Mid (3-5 yrs)
$102,000
to $126,000
Senior (6-9 yrs)
$132,000
to $156,000
Lead (10+ yrs)
$150,000
to $186,000
Salary trend
+7% YoYTotal compensation
Base salary is not the full picture. Equity, bonus, and signing can add $31,000 to the total package.
Base
$120,000
Equity
$18,000
Bonus
$11,000
Signing
$2,000
Estimated total: $151,000
How Charleston compares
Charleston, SC
$120,000
Cost of living: 2% below average
National Average
$118,000
Charleston is $2,000 above
Physician Assistant salary by city
Salary by role in Charleston
What you should know
Here is what the Physician Assistant market actually looks like in Charleston. Charleston is one of the South's fastest growing tech hubs, with Boeing, Volvo, and a wave of software companies establishing operations. The city's port drives significant logistics employment. Charleston's quality of life, moderate costs, and growing tech scene attract relocating professionals from across the country. Surgical subspecialties and emergency medicine pay the highest PA salaries, often 20 to 30% above primary care. Geographic location matters significantly, with rural and underserved areas offering premium pay to attract talent. Experience in procedural skills and first-assist certification further boost compensation.
Entry-level PAs earn $95,000 to $105,000 in their first role. Mid-career PAs with specialty experience reach $120,000 to $135,000. Senior PAs in surgical specialties or leadership positions can command $145,000 to $165,000 with additional administrative responsibilities. In Charleston, cost of living sits near the national average, so the numbers you see are roughly what you keep.
Base salary is not the full picture. PAs commonly receive productivity bonuses, CME allowances of $2,000 to $5,000 annually, malpractice insurance, and relocation assistance. Hospital systems often add shift differentials for nights, weekends, and call coverage. And on the tax side: south Carolina's top income tax rate is 6.4%. Charleston has no city income tax. The state rate is moderate, and the affordable cost of living keeps net pay competitive. When someone quotes you $120,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Highlight the Boeing and Volvo ecosystem when negotiating. Manufacturing and engineering employers in Charleston benchmark against national aerospace pay scales. The range for Physician Assistants in Charleston runs from $104,000 to $141,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology
Considering a related role?
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Common questions.
Physician Assistant salary in other cities
Other salaries in Charleston
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