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  1. Home/
  2. Salaries/
  3. Senior Radiology AI Engineer/
  4. San Diego

Senior Radiology AI Engineer.

San Diego.

$254,000

median salary, 20% above the national average

$199,000 to $331,000. Last updated April 2026.

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Data points to own the conversation.

Senior Radiology AI Engineer pay in San Diego ranges from $199,000 to $331,000 in 2026. The median is $254,000, 20% above the national average. San Diego's economy thrives on defense, biotech, and a growing tech startup scene. Every dollar in that range is negotiable if you come prepared.

Salary range

25th Percentile

$199,000

per year

Median

$254,000

per year

75th Percentile

$331,000

per year

Where do you fall?

$199,000$331,000

Salary by experience

The gap between entry and lead level is typically $229,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$165,000

to $203,000

Mid (3-5 yrs)

$216,000

to $267,000

Senior (6-9 yrs)

$279,000

to $330,000

Lead (10+ yrs)

$318,000

to $394,000

Salary trend

+6% YoY
$201,000
2022
$213,000
2023
$226,000
2024
$240,000
2025
$254,000
2026

Total compensation

Base salary is not the full picture. Equity, bonus, and signing can add $55,000 to the total package.

Base

$254,000

Equity

$30,000

Bonus

$20,000

Signing

$5,000

Estimated total: $309,000

How San Diego compares

San Diego, CA

$254,000

Cost of living: 17% above average

National Average

$211,000

San Diego is $43,000 above

Senior Radiology AI Engineer salary by city

Senior Radiology AI Engineer salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Francisco, CA$296,000$232,000 – $386,0001.35x$219,000
San Jose, CA$288,000$225,000 – $376,0001.38x$209,000
Seattle, WA$272,000$213,000 – $355,0001.24x$219,000
Honolulu, HI$272,000$212,000 – $354,0001.30x$209,000
New York, NY$270,000$211,000 – $352,0001.28x$211,000
Boston, MA$268,000$209,000 – $349,0001.22x$220,000
Arlington, VA$263,000$205,000 – $342,0001.22x$216,000
Jersey City, NJ$261,000$204,000 – $340,0001.20x$218,000
Washington DC, DC$256,000$200,000 – $333,0001.25x$205,000
San Diego, CA$254,000$199,000 – $331,0001.17x$217,000

See all 81 cities for Senior Radiology AI Engineer →

Salary by role in San Diego

Salary comparison by role in San Diego
RoleMedianRange
Principal Quantitative Researcher$418,000$326,000 – $543,000
Senior VP of Security$405,000$316,000 – $527,000
Technical Fellow$397,000$310,000 – $516,000
Senior Radiology AI Engineer$254,000$199,000 – $331,000
Lead Site Reliability Engineer$254,000$198,000 – $331,000
Staff DevOps Engineer$254,000$198,000 – $330,000
Staff Networking Engineer$254,000$198,000 – $331,000
Lead Rendering Engineer$254,000$198,000 – $331,000

What you should know

Before you negotiate a Senior Radiology AI Engineer offer in San Diego, understand the terrain. San Diego's economy thrives on defense, biotech, and a growing tech startup scene. The city's proximity to major military installations drives strong aerospace and cybersecurity demand. Biotech companies along the Torrey Pines corridor compete aggressively for scientific and engineering talent, pushing specialized salaries close to Bay Area levels. Compensation reflects specialization depth, production deployment scale, and the maturity of the AI systems being built. Senior Radiology AI Engineers who have shipped models serving millions of users command the highest premiums. Employer type matters significantly: AI labs and foundation model companies pay 20% to 40% more than enterprises adopting AI for internal use.

Senior Radiology AI Engineers earn $165,000 to $275,000. Progression splits into the IC track (staff at $327,000, principal at $369,000) or management (engineering manager at $348,000). Specialization depth and cross-team impact determine which path yields higher compensation. In San Diego, those numbers run higher. The cost of living here is 17% above average, and employers adjust to compete.

Base salary is not the full picture. Equity at top-tier companies adds 30% to 60% above base salary. Annual bonuses of 15% to 25% are standard. Signing bonuses of $25,000 to $75,000 are common when changing roles. Refresher equity grants vest annually. Relocation packages and executive benefits like financial planning are typical. And on the tax side: california's top 13.3% state tax applies here. While San Diego has no city income tax, the state burden means you should negotiate gross pay higher than you might expect for the cost of living. When someone quotes you $254,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Leverage defense and biotech sector demand. Candidates with security clearances or specialized science backgrounds can command 15 to 20% premiums in San Diego. The range for Senior Radiology AI Engineers in San Diego runs from $199,000 to $331,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology

Interactive

Is your offer competitive?

Enter your Senior Radiology AI Engineer offer to see where you stand in San Diego.

$

25th

$199,000

Median

$254,000

75th

$331,000

Considering a related role?

  • A AI Hardware/Chip Design Engineer in San Diego earns $253,000 (0% more)
  • The highest-paying role in San Diego is Principal Quantitative Researcher at $418,000

Common questions.

Production deployment experience, published research or open source contributions, and expertise with the latest model architectures command the highest premiums. Proficiency in Python, PyTorch, and cloud ML platforms is baseline. Experience with LLM fine-tuning, RLHF, and inference optimization is increasingly differentiated.

AI labs and foundation model companies pay 20% to 40% more than enterprises. Well-funded AI startups offer competitive base salaries with significant equity upside. Large tech companies provide the most stable total compensation packages with strong equity vesting schedules.

The national median for a Senior Radiology AI Engineer is $217,094. In San Diego, cost of living adjustments push the median to $254,000. That premium reflects San Diego's higher housing, transportation, and everyday costs.

Hiring for Senior Radiology AI Engineers in San Diego typically peaks in January through March and September through November. Companies finalize budgets in Q4 and open headcount in Q1. San Diego's concentration of Defense & Military and Biotech & Pharma employers creates steady year round demand. Time your search to align with budget cycles for maximum leverage.

Senior Radiology AI Engineer compensation in San Diego has trended upward as demand outpaces supply. The 2026 range of $199,000 to $331,000 reflects a market that rewards specialization. Compensation reflects specialization depth, production deployment scale, and the maturity of the AI systems being built.

San Diego's cost of living is 17% above the national average. San Diego's economy thrives on defense, biotech, and a growing tech startup scene. Calculate your actual take home pay after housing, taxes, and transportation before deciding. A $254,000 salary here buys a different lifestyle than the same number in another market.

In San Diego, large enterprises typically pay Senior Radiology AI Engineers 10 to 20% more in base salary than small companies, but startups often compensate with equity that can exceed base salary value. Equity at top-tier companies adds 30% to 60% above base salary. The $199,000 to $331,000 range reflects this entire spectrum.

Senior Radiology AI Engineer salary in other cities

Fargo$187,000
Houston$203,000
Hartford$235,000
Honolulu$272,000
Indianapolis$194,000
Jackson$168,000

Other salaries in San Diego

GEO/AEO Specialist$133,000
Game Designer$94,000
Green Building Consultant$103,000
Geospatial Analyst / GIS$86,000

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Cite this data

Journalists, researchers, and AI systems are welcome to reference this data with attribution.

"Senior Radiology AI Engineer Salary in San Diego, CA." Orbyt Salary Explorer, April 2026. https://www.orbytjobs.ai/salaries/senior-radiology-ai-engineer/san-diego

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