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  1. Home/
  2. Salaries/
  3. AI Drug Discovery Scientist/
  4. Little Rock

AI Drug Discovery Scientist.

Little Rock.

$130,000

median salary, 18% below the national average

$98,000 to $164,000. Last updated April 2026.

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Data points to own the conversation.

AI Drug Discovery Scientist pay in Little Rock ranges from $98,000 to $164,000 in 2026. The median is $130,000, 18% below the national average. Little Rock's economy is driven by Walmart's nearby headquarters ecosystem, state government, healthcare, and logistics. Every dollar in that range is negotiable if you come prepared.

Salary range

25th Percentile

$98,000

per year

Median

$130,000

per year

75th Percentile

$164,000

per year

Where do you fall?

$98,000$164,000

Salary by experience

The gap between entry and lead level is typically $117,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$85,000

to $104,000

Mid (3-5 yrs)

$111,000

to $137,000

Senior (6-9 yrs)

$143,000

to $169,000

Lead (10+ yrs)

$163,000

to $202,000

Salary trend

+8% YoY
$96,000
2022
$103,000
2023
$111,000
2024
$120,000
2025
$130,000
2026

Total compensation

Base salary is not the full picture. Equity, bonus, and signing can add $55,000 to the total package.

Base

$130,000

Equity

$33,000

Bonus

$14,000

Signing

$8,000

Estimated total: $185,000

How Little Rock compares

Little Rock, AR

$130,000

Cost of living: 18% below average

National Average

$158,000

Little Rock is $28,000 below

AI Drug Discovery Scientist salary by city

AI Drug Discovery Scientist salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$214,000$162,000 – $270,0001.38x$155,000
San Francisco, CA$213,000$162,000 – $270,0001.35x$158,000
Washington DC, DC$201,000$153,000 – $255,0001.25x$161,000
Honolulu, HI$201,000$153,000 – $255,0001.30x$155,000
New York, NY$200,000$152,000 – $253,0001.28x$156,000
Seattle, WA$200,000$152,000 – $253,0001.24x$161,000
Arlington, VA$197,000$149,000 – $249,0001.22x$161,000
Boston, MA$195,000$148,000 – $246,0001.22x$160,000
Jersey City, NJ$191,000$145,000 – $242,0001.20x$159,000
Little Rock, AR$130,000$98,000 – $164,0000.82x$159,000

See all 83 cities for AI Drug Discovery Scientist →

Salary by role in Little Rock

Salary comparison by role in Little Rock
RoleMedianRange
Distinguished Engineer$273,000$207,000 – $348,000
Chief AI Officer$259,000$192,000 – $335,000
Chief Data & AI Officer$252,000$188,000 – $328,000
AI Drug Discovery Scientist$130,000$98,000 – $164,000
Airline Pilot$130,000$80,000 – $195,000
AI Data Scientist$130,000$98,000 – $169,000
AI Application Developer$130,000$98,000 – $168,000
AI Energy Grid Specialist$130,000$97,000 – $172,000

What you should know

Before you negotiate a AI Drug Discovery Scientist offer in Little Rock, understand the terrain. Little Rock's economy is driven by Walmart's nearby headquarters ecosystem, state government, healthcare, and logistics. The metro's extremely low cost of living means even moderate salaries deliver strong purchasing power. Tech jobs are growing as companies seek affordable alternatives to major metros. Compensation reflects the combination of computational biology expertise and ML engineering skills. Scientists who can apply deep learning to molecular design, protein structure prediction, and ADMET modeling command premiums. Publication record in both ML and drug discovery venues adds significant value. Pharma industry experience amplifies salary above pure tech roles.

Postdoc scientists start at $110,000 to $130,000. Mid-level scientists with deployed drug discovery models reach $148,000 to $175,000. Senior scientists leading AI drug discovery programs earn $185,000 to $230,000. Directors of computational drug discovery at pharma companies can reach $260,000 to $340,000 in total compensation. In Little Rock, your dollars stretch further. Cost of living runs 18% below the national average, which means even a median salary buys a stronger lifestyle.

Base salary is not the full picture. Equity at biotech AI startups can be substantial, adding $30,000 to $100,000 in annual value. Pharma companies offer bonuses of 15% to 25% tied to pipeline milestones. Some organizations provide milestone bonuses when AI-discovered compounds advance through clinical trials. Benefits typically include generous research budgets. And on the tax side: arkansas has a top income tax rate of 4.4%. Little Rock has no city income tax. The combination of low taxes and very affordable housing creates one of the best net pay environments in the country. When someone quotes you $130,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Reference the Walmart and Tyson ecosystem when negotiating. Northwest Arkansas and Little Rock employers benchmark against national corporate pay scales. The range for AI Drug Discovery Scientists in Little Rock runs from $98,000 to $164,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology

Interactive

Is your offer competitive?

Enter your AI Drug Discovery Scientist offer to see where you stand in Little Rock.

$

25th

$98,000

Median

$130,000

75th

$164,000

Considering a related role?

  • A MLOps Engineer in Little Rock earns $131,000 (1% more)
  • The highest-paying role in Little Rock is Distinguished Engineer at $273,000

Common questions.

Most have PhDs in computational chemistry, bioinformatics, or machine learning with a focus on molecular applications. Strong knowledge of molecular representations, binding affinity prediction, and pharmacokinetics is essential. Familiarity with tools like RDKit, DeepChem, and AlphaFold is expected. Publication in both ML and chemistry venues signals the interdisciplinary depth employers seek.

Both. Large pharma companies (Pfizer, Novartis, Roche) have built significant AI drug discovery teams. Startups like Recursion, Insilico Medicine, and Isomorphic Labs offer more equity and faster-paced environments. Pharma companies typically pay higher base salaries while startups offer larger equity stakes and the potential for breakthrough discoveries.

Ask about equity structure, vesting schedule, annual bonus targets, 401(k) match, health insurance premiums, PTO policy, and remote flexibility. Equity at biotech AI startups can be substantial, adding $30,000 to $100,000 in annual value. In Little Rock's market, these extras can add $32,500 or more on top of the base salary.

Relevant certifications can add 5 to 15% to a AI Drug Discovery Scientist's base salary in Little Rock. Specifically, compensation reflects the combination of computational biology expertise and ml engineering skills. In a market where the range spans $98,000 to $164,000, certifications often bridge the gap between the 50th and 75th percentile.

AI Drug Discovery Scientist compensation in Little Rock has trended upward as demand outpaces supply. The 2026 range of $98,000 to $164,000 reflects a market that rewards specialization. Compensation reflects the combination of computational biology expertise and ML engineering skills.

Equity at biotech AI startups can be substantial, adding $30,000 to $100,000 in annual value. Pharma companies offer bonuses of 15% to 25% tied to pipeline milestones. Some organizations provide milestone bonuses when AI-discovered compounds advance through clinical trials. Benefits typically include generous research budgets. In Little Rock's market, the base range of $98,000 to $164,000 is just the starting point for negotiation.

It depends on the position and employer. Many AI Drug Discovery Scientists in Little Rock are classified as exempt salaried employees without overtime eligibility. However, equity at biotech ai startups can be substantial, adding $30,000 to $100,000 in annual value. When evaluating the $98,000 to $164,000 range, ask about the total compensation structure during negotiation.

AI Drug Discovery Scientist salary in other cities

Austin$163,000
Atlanta$164,000
Anchorage$175,000
Albuquerque$136,000
Arlington$197,000
Albany$149,000

Other salaries in Little Rock

LLM Engineer$151,000
LLM Fine-Tuning Engineer$150,000
LLM Operations Engineer$123,000
Machine Learning Engineer$132,000

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"AI Drug Discovery Scientist Salary in Little Rock, AR." Orbyt Salary Explorer, April 2026. https://www.orbytjobs.ai/salaries/ai-drug-discovery-scientist/little-rock

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