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  1. Home/
  2. Salaries/
  3. Clinical AI Engineer/
  4. Madison

Clinical AI Engineer.

Madison.

$132,000

median salary, 9% below the national average

$100,000 to $169,000. Last updated April 2026.

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Data points to own the conversation.

The median Clinical AI Engineer salary in Madison is $132,000, 9% below the national average. Entry level starts near $100,000. Experienced professionals push past $169,000. Madison is a growing tech hub anchored by the University of Wisconsin and Epic Systems, one of the largest health IT companies. That spread is your negotiation window.

Salary range

25th Percentile

$100,000

per year

Median

$132,000

per year

75th Percentile

$169,000

per year

Where do you fall?

$100,000$169,000

Salary by experience

The gap between entry and lead level is typically $119,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$86,000

to $106,000

Mid (3-5 yrs)

$112,000

to $139,000

Senior (6-9 yrs)

$145,000

to $172,000

Lead (10+ yrs)

$165,000

to $205,000

Salary trend

+6% YoY
$105,000
2022
$111,000
2023
$117,000
2024
$125,000
2025
$132,000
2026

Total compensation

Base salary is not the full picture. Equity, bonus, and signing can add $30,000 to the total package.

Base

$132,000

Equity

$16,000

Bonus

$11,000

Signing

$3,000

Estimated total: $162,000

How Madison compares

Madison, WI

$132,000

Cost of living: 5% below average

National Average

$145,000

Madison is $13,000 below

Clinical AI Engineer salary by city

Clinical AI Engineer salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Francisco, CA$202,000$153,000 – $257,0001.35x$150,000
San Jose, CA$192,000$146,000 – $245,0001.38x$139,000
Honolulu, HI$190,000$144,000 – $243,0001.30x$146,000
New York, NY$180,000$137,000 – $230,0001.28x$141,000
Arlington, VA$179,000$136,000 – $228,0001.22x$147,000
San Diego, CA$175,000$133,000 – $223,0001.17x$150,000
Washington DC, DC$174,000$132,000 – $222,0001.25x$139,000
Seattle, WA$173,000$131,000 – $220,0001.24x$140,000
Newark, NJ$173,000$131,000 – $220,0001.18x$147,000
Madison, WI$132,000$100,000 – $169,0000.95x$139,000

See all 83 cities for Clinical AI Engineer →

Salary by role in Madison

Salary comparison by role in Madison
RoleMedianRange
Distinguished Engineer$307,000$233,000 – $391,000
Chief AI Officer$303,000$225,000 – $391,000
Chief Technology Officer$273,000$202,000 – $357,000
Clinical AI Engineer$132,000$100,000 – $169,000
Mobile Developer$132,000$101,000 – $171,000
Design Engineer$132,000$101,000 – $172,000
AI Real Estate/PropTech Specialist$132,000$98,000 – $178,000
Simulation Engineer$132,000$101,000 – $168,000

What you should know

Before you negotiate a Clinical AI Engineer offer in Madison, understand the terrain. Madison is a growing tech hub anchored by the University of Wisconsin and Epic Systems, one of the largest health IT companies. The city consistently ranks among the best places to live and has a thriving startup ecosystem. Salaries are competitive relative to the modest cost of living. Compensation reflects the specialized intersection of ML engineering and clinical domain expertise. Engineers who can navigate FDA regulatory requirements, build AI systems for clinical decision support, and validate models against clinical outcomes earn premiums. Experience with medical imaging AI, EHR integration, or clinical NLP adds significant value.

Junior clinical AI engineers start at $100,000 to $115,000. Mid-level engineers building FDA-ready AI systems reach $135,000 to $165,000. Senior engineers leading clinical AI programs earn $170,000 to $210,000. Directors of clinical AI at hospital systems or health tech companies can reach $230,000 to $290,000 in total compensation. In Madison, cost of living sits near the national average, so the numbers you see are roughly what you keep.

Base salary is not the full picture. Equity at health AI startups adds $20,000 to $70,000 annually. Bonuses of 10% to 20% are standard. Benefits often include continuing medical education stipends and conference budgets. Some healthcare systems offer pension benefits and loan forgiveness programs. And on the tax side: wisconsin's top income tax rate is 7.65%. Madison has no city income tax. The moderate state rate is offset by the affordable cost of living and strong employer base. When someone quotes you $132,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Reference Epic Systems compensation benchmarks. Epic sets the salary standard for tech in Madison and most employers in the area compete against their packages. The range for Clinical AI Engineers in Madison runs from $100,000 to $169,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology

Interactive

Is your offer competitive?

Enter your Clinical AI Engineer offer to see where you stand in Madison.

$

25th

$100,000

Median

$132,000

75th

$169,000

Considering a related role?

  • A Conversational AI Designer in Madison earns $133,000 (1% more)
  • The highest-paying role in Madison is Distinguished Engineer at $307,000

Common questions.

Medical training is not required but clinical domain knowledge is essential. Most clinical AI engineers have engineering or computer science backgrounds with specialized training in clinical informatics or biomedical engineering. Working closely with clinicians during development is standard practice. Certifications in clinical informatics or health IT demonstrate domain commitment.

Significantly. AI systems used in clinical decision-making require FDA clearance (510(k) or De Novo), which demands rigorous validation, documentation, and post-market monitoring. Engineers must understand Good Machine Learning Practice, predetermined change control plans, and real-world performance monitoring. This regulatory knowledge is a career differentiator that justifies higher compensation.

Many Madison employers are shifting toward skills based hiring for Clinical AI Engineer positions. While a degree can accelerate your path to the median salary of $132,000, demonstrated experience, certifications, and a strong portfolio carry significant weight. Candidates without degrees may start closer to $100,000 but can reach the 75th percentile with three to five years of proven results.

Lead with data: Clinical AI Engineers in Madison earn $100,000 to $169,000, so anchoring your ask near $169,000 gives room to land at the median. Reference Epic Systems compensation benchmarks. Epic sets the salary standard for tech in Madison and most employers in the area compete against their packages. Never accept the first number without a conversation.

The national median for a Clinical AI Engineer is $138,947. In Madison, cost of living adjustments push the median to $132,000. That discount reflects Madison's lower housing, transportation, and everyday costs.

Clinical AI Engineer salary in other cities

Indianapolis$132,000
Jackson$117,000
Jersey City$172,000
Kansas City$136,000
Knoxville$125,000
Los Angeles$169,000

Other salaries in Madison

Blockchain Developer$146,000
Behavioral Health Tech$35,000
Business Analyst$84,000
Brand Strategist$90,000

Related

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Cite this data

Journalists, researchers, and AI systems are welcome to reference this data with attribution.

"Clinical AI Engineer Salary in Madison, WI." Orbyt Salary Explorer, April 2026. https://www.orbytjobs.ai/salaries/clinical-ai-engineer/madison

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