Clinical Research Coordinator.
Des Moines.
$57,000
median salary, 11% below the national average
$44,000 to $73,000. Last updated April 2026.
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Data points to own the conversation.
A Clinical Research Coordinator in Des Moines earns a median of $57,000 in 2026. That is 11% below the national average. The range runs from $44,000 to $73,000, and where you land depends on your experience, your skills, and how well you negotiate. Therapeutic area and trial phase drive the biggest pay differences.
Salary range
Where do you fall?
Salary by experience
The gap between entry and lead level is typically $51,000. Where you land depends on years of experience and what you bring to the table.
Entry (0-2 yrs)
$37,000
to $46,000
Mid (3-5 yrs)
$48,000
to $60,000
Senior (6-9 yrs)
$63,000
to $74,000
Lead (10+ yrs)
$71,000
to $88,000
Salary trend
+8% YoYTotal compensation
Base salary is not the full picture. Equity, bonus, and signing can add $11,000 to the total package.
Base
$57,000
Equity
$6,000
Bonus
$4,000
Signing
$1,000
Estimated total: $68,000
How Des Moines compares
Des Moines, IA
$57,000
Cost of living: 14% below average
National Average
$64,000
Des Moines is $7,000 below
Clinical Research Coordinator salary by city
Salary by role in Des Moines
What you should know
The Clinical Research Coordinator landscape in Des Moines is not what most salary sites will tell you. Des Moines is a major insurance and financial services hub, home to Principal Financial, EMC Insurance, and a growing fintech community. The metro's extremely low cost of living and strong job market make it one of the best value cities for finance professionals. Tech employment is growing as insurtech companies expand. Therapeutic area and trial phase drive the biggest pay differences. Oncology, gene therapy, and Phase I trials pay the most due to protocol complexity. ACRP or SoCRA certification adds 8 to 12% above non-certified coordinators. Academic medical centers and large CROs in biotech hubs offer the highest salaries.
Entry-level CRCs start at $48,000 to $55,000 with a science degree. Certified CRCs with three to five years of experience earn $65,000 to $80,000. Senior CRCs or clinical research managers can reach $85,000 to $110,000 overseeing multi-site trials and regulatory submissions. In Des Moines, your dollars stretch further. Cost of living runs 14% below the national average, which means even a median salary buys a stronger lifestyle.
Base salary is not the full picture. CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. CRO-employed coordinators may receive project completion bonuses of $2,000 to $5,000. Some pharmaceutical sponsors offer annual merit increases of 3 to 6%. And on the tax side: iowa has a flat 3.8% state income tax. Des Moines has no city income tax. The low tax rate and affordable housing create strong purchasing power. When someone quotes you $57,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Benchmark against national insurance industry pay scales. Des Moines insurance employers must compete with remote offers from larger metros and will often match. The range for Clinical Research Coordinators in Des Moines runs from $44,000 to $73,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology
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Common questions.
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