Physician Assistant.
Indianapolis.
$106,000
median salary, 10% below the national average
$92,000 to $124,000. Last updated April 2026.
Get the job.
Data points to own the conversation.
If you are evaluating a Physician Assistant offer in Indianapolis, IN, here is the reality: $92,000 to $124,000, with $106,000 as the midpoint. 10% below the national average. Surgical subspecialties and emergency medicine pay the highest PA salaries, often 20 to 30% above primary care. Do not accept the first number.
Salary range
Where do you fall?
Salary by experience
The gap between entry and lead level is typically $95,000. Where you land depends on years of experience and what you bring to the table.
Entry (0-2 yrs)
$69,000
to $85,000
Mid (3-5 yrs)
$90,000
to $111,000
Senior (6-9 yrs)
$117,000
to $138,000
Lead (10+ yrs)
$133,000
to $164,000
Salary trend
+7% YoYTotal compensation
Base salary is not the full picture. Equity, bonus, and signing can add $28,000 to the total package.
Base
$106,000
Equity
$16,000
Bonus
$10,000
Signing
$2,000
Estimated total: $134,000
How Indianapolis compares
Indianapolis, IN
$106,000
Cost of living: 9% below average
National Average
$118,000
Indianapolis is $12,000 below
Physician Assistant salary by city
Salary by role in Indianapolis
What you should know
Here is what the Physician Assistant market actually looks like in Indianapolis. Indianapolis has a diversified economy led by healthcare, life sciences, and motorsports engineering. Eli Lilly's headquarters drives a major pharmaceutical and biotech cluster. The city's extremely affordable cost of living means that even moderate salaries deliver strong purchasing power, making it an underrated destination for professionals seeking financial stability. Surgical subspecialties and emergency medicine pay the highest PA salaries, often 20 to 30% above primary care. Geographic location matters significantly, with rural and underserved areas offering premium pay to attract talent. Experience in procedural skills and first-assist certification further boost compensation.
Entry-level PAs earn $95,000 to $105,000 in their first role. Mid-career PAs with specialty experience reach $120,000 to $135,000. Senior PAs in surgical specialties or leadership positions can command $145,000 to $165,000 with additional administrative responsibilities. In Indianapolis, cost of living sits near the national average, so the numbers you see are roughly what you keep.
Base salary is not the full picture. PAs commonly receive productivity bonuses, CME allowances of $2,000 to $5,000 annually, malpractice insurance, and relocation assistance. Hospital systems often add shift differentials for nights, weekends, and call coverage. And on the tax side: indiana has a flat 3.05% state income tax, one of the lowest in the country. Marion County adds about 2.02% in local taxes. The combined rate remains well below most major metros. When someone quotes you $106,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Benchmark against pharmaceutical industry pay scales. Eli Lilly and the biotech cluster set high compensation floors that ripple across all professional roles in Indianapolis. The range for Physician Assistants in Indianapolis runs from $92,000 to $124,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology
Considering a related role?
- A IT Project Manager in Indianapolis earns $105,000 (1% less)
- The highest-paying role in Indianapolis is Chief AI Officer at $293,000
Common questions.
Physician Assistant salary in other cities
Other salaries in Indianapolis
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