Registered Nurse.
Des Moines.
$69,000
median salary, 16% below the national average
$52,000 to $88,000. Last updated April 2026.
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Data points to own the conversation.
Des Moines is 14% cheaper than the national average. For Registered Nurses, that shakes out to a median of $69,000, with the full range spanning $52,000 to $88,000. Specialty certification, geographic location, and facility type create the widest salary ranges. Know the range before you walk in.
Salary range
Where do you fall?
Salary by experience
The gap between entry and lead level is typically $62,000. Where you land depends on years of experience and what you bring to the table.
Entry (0-2 yrs)
$45,000
to $55,000
Mid (3-5 yrs)
$59,000
to $72,000
Senior (6-9 yrs)
$76,000
to $90,000
Lead (10+ yrs)
$86,000
to $107,000
Salary trend
+5% YoYTotal compensation
Base salary is not the full picture. Equity, bonus, and signing can add $20,000 to the total package.
Base
$69,000
Equity
$12,000
Bonus
$7,000
Signing
$1,000
Estimated total: $89,000
How Des Moines compares
Des Moines, IA
$69,000
Cost of living: 14% below average
National Average
$82,000
Des Moines is $13,000 below
Registered Nurse salary by city
Salary by role in Des Moines
What you should know
Here is what the Registered Nurse market actually looks like in Des Moines. Des Moines is a major insurance and financial services hub, home to Principal Financial, EMC Insurance, and a growing fintech community. The metro's extremely low cost of living and strong job market make it one of the best value cities for finance professionals. Tech employment is growing as insurtech companies expand. Specialty certification, geographic location, and facility type create the widest salary ranges. ICU, OR, and emergency nurses earn premiums over med surg nurses. Travel nursing contracts can pay 50 to 100% more than permanent positions. Union representation and shift differentials for nights and weekends also impact total pay.
New graduate RNs start at $58,000 to $72,000, with experienced RNs reaching $80,000 to $100,000 after five years. Nurse practitioners earn $110,000 to $140,000, and CRNAs (nurse anesthetists) can earn $180,000 to $220,000. Nursing management roles offer $95,000 to $140,000 with administrative responsibilities. In Des Moines, your dollars stretch further. Cost of living runs 14% below the national average, which means even a median salary buys a stronger lifestyle.
Base salary is not the full picture. Benefits are a major component, typically including health insurance, pension or 403(b) matching, tuition reimbursement, and continuing education credits. Shift differentials add $3 to $8 per hour for nights and weekends. Signing bonuses of $5,000 to $20,000 are common in high demand specialties. And on the tax side: iowa has a flat 3.8% state income tax. Des Moines has no city income tax. The low tax rate and affordable housing create strong purchasing power. When someone quotes you $69,000, ask what the total package looks like. The gap between base and total comp is where real money hides.
On negotiation: Benchmark against national insurance industry pay scales. Des Moines insurance employers must compete with remote offers from larger metros and will often match. The range for Registered Nurses in Des Moines runs from $52,000 to $88,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.
Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology
Considering a related role?
- A Data Analyst in Des Moines earns $68,000 (1% less)
- The highest-paying role in Des Moines is Chief AI Officer at $277,000
Common questions.
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