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  1. Home/
  2. Salaries/
  3. Synthetic Biology AI Researcher/
  4. Los Angeles

Synthetic Biology AI Researcher.

Los Angeles.

$254,000

median salary, 15% above the national average

$199,000 to $331,000. Last updated April 2026.

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Data points to own the conversation.

The median Synthetic Biology AI Researcher salary in Los Angeles is $254,000, 15% above the national average. Entry level starts near $199,000. Experienced professionals push past $331,000. Los Angeles blends a thriving entertainment industry with a growing tech and startup ecosystem, often called Silicon Beach. That spread is your negotiation window.

Salary range

25th Percentile

$199,000

per year

Median

$254,000

per year

75th Percentile

$331,000

per year

Where do you fall?

$199,000$331,000

Salary by experience

The gap between entry and lead level is typically $229,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$165,000

to $203,000

Mid (3-5 yrs)

$216,000

to $267,000

Senior (6-9 yrs)

$279,000

to $330,000

Lead (10+ yrs)

$318,000

to $394,000

Salary trend

+4% YoY
$217,000
2022
$226,000
2023
$235,000
2024
$244,000
2025
$254,000
2026

Total compensation

Base salary is not the full picture. Equity, bonus, and signing can add $71,000 to the total package.

Base

$254,000

Equity

$41,000

Bonus

$25,000

Signing

$5,000

Estimated total: $325,000

How Los Angeles compares

Los Angeles, CA

$254,000

Cost of living: 18% above average

National Average

$220,000

Los Angeles is $34,000 above

Synthetic Biology AI Researcher salary by city

Synthetic Biology AI Researcher salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$291,000$228,000 – $379,0001.38x$211,000
Honolulu, HI$289,000$226,000 – $376,0001.30x$222,000
San Francisco, CA$288,000$225,000 – $375,0001.35x$213,000
New York, NY$273,000$214,000 – $355,0001.28x$213,000
Washington DC, DC$272,000$213,000 – $354,0001.25x$218,000
Jersey City, NJ$269,000$211,000 – $350,0001.20x$224,000
Arlington, VA$268,000$210,000 – $349,0001.22x$220,000
Princeton, NJ$263,000$206,000 – $342,0001.15x$229,000
Boulder, CO$263,000$206,000 – $342,0001.15x$229,000
Los Angeles, CA$254,000$199,000 – $331,0001.18x$215,000

See all 81 cities for Synthetic Biology AI Researcher →

Salary by role in Los Angeles

Salary comparison by role in Los Angeles
RoleMedianRange
Technical Fellow$430,000$335,000 – $558,000
Principal Quantitative Researcher$417,000$325,000 – $542,000
Principal AI Research Scientist$405,000$316,000 – $526,000
Synthetic Biology AI Researcher$254,000$199,000 – $331,000
Lead Search Engineer$254,000$198,000 – $331,000
Staff Networking Engineer$254,000$198,000 – $331,000
Senior AWS Solutions Architect$254,000$199,000 – $331,000
Lead Multi-Cloud Engineer$254,000$198,000 – $331,000

What you should know

If you are interviewing for Synthetic Biology AI Researcher roles in Los Angeles, here is what you are walking into. Los Angeles blends a thriving entertainment industry with a growing tech and startup ecosystem, often called Silicon Beach. The city's diverse economy spans aerospace, healthcare, fashion, and gaming. LA offers strong salaries that, while below San Francisco levels, pair with a broader lifestyle appeal and lower housing costs relative to the Bay Area. Compensation reflects specialization depth, production deployment scale, and the maturity of the AI systems being built. Synthetic Biology AI Researchers who have shipped models serving millions of users command the highest premiums. Employer type matters significantly: AI labs and foundation model companies pay 20% to 40% more than enterprises adopting AI for internal use.

Entry-level Synthetic Biology AI Researchers start near $172,000. Mid-career professionals with three to five years of experience reach $220,000 to $286,000. Senior-level roles command $282,000 to $341,000. Management transitions to director-level positions offer $363,000 and above. In Los Angeles, those numbers run higher. The cost of living here is 18% above average, and employers adjust to compete.

Base salary is not the full picture. Equity at top-tier companies adds 30% to 60% above base salary. Annual bonuses of 15% to 25% are standard. Signing bonuses of $25,000 to $75,000 are common when changing roles. Refresher equity grants vest annually. Relocation packages and executive benefits like financial planning are typical. And on the tax side: california's 13.3% top state income tax rate applies to LA earners as well. There is no city income tax, but the high state rate makes take home pay lower than cities in no income tax states. When someone quotes you $254,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Highlight cross industry skills. LA employers value candidates who bridge entertainment and tech, so framing your experience across verticals can unlock higher offers. The range for Synthetic Biology AI Researchers in Los Angeles runs from $199,000 to $331,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: SEC filings, H-1B LCA (DOL), BLS OES, 50+ job posting platforms. COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified April 8, 2026. Full methodology

Interactive

Is your offer competitive?

Enter your Synthetic Biology AI Researcher offer to see where you stand in Los Angeles.

$

25th

$199,000

Median

$254,000

75th

$331,000

Considering a related role?

  • A Transformer Architecture Engineer in Los Angeles earns $255,000 (0% more)
  • The highest-paying role in Los Angeles is Technical Fellow at $430,000

Common questions.

Production deployment experience, published research or open source contributions, and expertise with the latest model architectures command the highest premiums. Proficiency in Python, PyTorch, and cloud ML platforms is baseline. Experience with LLM fine-tuning, RLHF, and inference optimization is increasingly differentiated.

AI labs and foundation model companies pay 20% to 40% more than enterprises. Well-funded AI startups offer competitive base salaries with significant equity upside. Large tech companies provide the most stable total compensation packages with strong equity vesting schedules.

In Los Angeles, large enterprises typically pay Synthetic Biology AI Researchers 10 to 20% more in base salary than small companies, but startups often compensate with equity that can exceed base salary value. Equity at top-tier companies adds 30% to 60% above base salary. The $199,000 to $331,000 range reflects this entire spectrum.

Synthetic Biology AI Researcher hiring in Los Angeles typically involves three to five rounds: a recruiter screen, a technical or skills assessment, one or two team interviews, and a final conversation with leadership. Companies in Los Angeles's Entertainment & Media sector may add domain specific evaluations. The process usually takes two to four weeks. Prepare by researching the company and practicing with Orbyt's Interview Prep tool.

The national median for a Synthetic Biology AI Researcher is $215,254. In Los Angeles, cost of living adjustments push the median to $254,000. That premium reflects Los Angeles's higher housing, transportation, and everyday costs.

Synthetic Biology AI Researcher salary in other cities

Austin$236,000
Atlanta$224,000
Anchorage$241,000
Albuquerque$201,000
Arlington$268,000
Albany$215,000

Other salaries in Los Angeles

Accountant$82,000
Applied AI Researcher$210,000
Agentic Orchestrator$245,000
Autonomous Systems Engineer$230,000

Related

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"Synthetic Biology AI Researcher Salary in Los Angeles, CA." Orbyt Salary Explorer, April 2026. https://www.orbytjobs.ai/salaries/synthetic-biology-ai-researcher/los-angeles

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